Tag Archives: ERK1/2 (extracellular signal?Cregulated kinases one and two)

KRAS or BRAF will underpin acquired resistance to MEK1/2 inhibitors in colorectal cancer cells

Little AS, Balmanno K, Sale MJ, Newman S, Dry JR, Hampson M, Edwards PA, Smith PD, Cook SJ. “Sci Signal. 2011″ Background: The acquisition of resistance to protein kinase inhibitors is actually a expanding dilemma in cancer remedy. We modeled … Continue reading

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